Product Category
Immunomodulatory & Cytoprotective Tripeptides
Action on the Human Body
KPV (Lysine-Proline-Valine) is a highly stable C-terminal tripeptide fragment of alpha-Melanocyte Stimulating Hormone ($alpha$-MSH). It exerts potent, non-immunosuppressive anti-inflammatory actions by entering cells and directly counteracting the NF-$kappa$B transcription signaling loop. By neutralizing this master switch, KPV suppresses the production of pro-inflammatory cytokines, including IL-1$beta$, IL-6, and TNF-$alpha$. Additionally, KPV lowers the expression of vascular adhesion molecules to curb inflammatory white blood cell migration. It demonstrates natural antimicrobial properties against pathogens like *Candida albicans*, maintains strict structural integrity across intestinal tight junctions, and downregulates collagen overproduction to prevent scarring in injured tissues.
What to Expect if Consumed
Users notice a rapid easing of digestive discomfort or flare-ups, reduced skin irritation, a significant drop in systemic swelling, and quicker recovery from chronic inflammatory episodes.
Possible Therapy Combinations
Pairs exquisitely with BPC-157 to form a powerful gut-healing and tissue-repair protocol, or combined with LL-37 to manage complex inflammatory GI issues and clean up underlying bacterial imbalance.
Molecular Formula & Chemical Composition
Sequence: Lys-Pro-Val. Molecular Formula: C16H30N4O4. Purity: >99% Analytical Grade Lyophilized Mass via strict HPLC validation.
WARNING: This peptide compound must be handled and utilized exclusively under very high, correct professional and qualified medical supervision. Misuse can lead to unintended biological variations.
Scientific References
1. Catania, A., et al. (2004). ‘The anti-inflammatory tripeptide KPV: Mechanisms and therapeutic potential.’ Trends in Pharmacological Sciences.
2. Dalmasso, G., et al. (2008). ‘PepT1-mediated transport of the anti-inflammatory tripeptide KPV ameliorates intestinal inflammation in models of colitis.’ Gastroenterology.
Why choose our KPV, 5mg?
- Guaranteed 99%+ Purity: Synthesized specifically for rigorous laboratory and analytical research.
- Strict Quality Control: Verified via HPLC and MS testing to ensure precise molecular concentration.
- Secure & Stable Shipping: Packaged carefully to maintain compound stability during transit.
Note: This product is sold exclusively for laboratory research purposes only. It is not intended for human or veterinary use.
