AOD-9604, 5mg

Product Category

Targeted Lipolytic Peptides & Cartilage Modifying Fragments

Action on the Human Body

AOD-9604 (Advanced Obesity Drug 9604) is a synthetic 16-amino acid peptide analog mimicking the C-terminal lipolytic domain of human Growth Hormone (hGH residues 177-191) with an added stabilizing tyrosine residue. It works by binding selectively to beta-3 adrenergic receptors on adipocytes, stimulating adenylate cyclase to elevate cyclic AMP (cAMP) levels, which directly initiates fat degradation (lipolysis) and blocks fat storage pathways (lipogenesis). Crucially, AOD-9604 lacks the N-terminal sequence responsible for binding to the insulin-like growth factor-1 (IGF-1) receptor. Consequently, it delivers robust adipose destruction without altering plasma glucose levels, provoking insulin resistance, or inducing systemic growth cascades. Beyond fat management, recent biological models demonstrate it stimulates proteoglycan and collagen production within damaged cartilage, assisting in structural joint matrix protection.