Product Category
Second-Generation Growth Hormone Releasing Hormone (GHRH) Analogs
Action on the Human Body
CJC-1295 No DAC (also known as Mod GRF 1-29) is a highly optimized synthetic peptide analog of endogenous Growth Hormone Releasing Hormone (GHRH). By introducing specific amino acid substitutions at positions 2, 8, 15, and 27, this molecule achieves enhanced resistance to enzymatic cleavage by dipeptidyl peptidase-4 (DPP-4), extending its active window to roughly 30 minutes. It binds specifically to pituitary GHRH receptors, activating cAMP and calcium-dependent signaling cascades to amplify the amplitude of natural, pulsatile growth hormone (GH) releases. This surge elevates circulating levels of IGF-1, resulting in accelerated fat loss via lipolysis, enhanced cellular protein synthesis, robust connective tissue healing, and improved physical recovery profiles while fully preserving native hypothalamic-pituitary-somatotropic rhythmicity.






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