Cagrilintide, 5mg

Product Category

Long-Acting Amylin Analogs & Satiety Signaling Modulators

Action on the Human Body

Cagrilintide is a long-acting, synthetic acylated analog of endogenous amylin, a neuroendocrine peptide co-secreted with insulin by pancreatic beta cells. It works as a non-selective agonist at amylin receptors (AMY) and calcitonin receptors, targeting areas within the central nervous system—specifically the area postrema in the hindbrain—to induce powerful, long-lasting satiation signaling. Cagrilintide slows the rate of gastric emptying, delays postprandial glucose transitions, and directly down-regulates hedonic food intake mechanisms (cravings). Due to its specific lipid-conjugation (acylation), it binds strongly to plasma albumin, providing an extended therapeutic half-life. It acts as a primary metabolic tool that shifts nutrient utilization, suppresses appetite, and optimizes fat mass management profiles.