Tesofensine, 500mcg

Product Category

Monoamine Reuptake Inhibitors, Central Satiety Factors & Metabolic Enhancers

Action on the Human Body

Tesofensine (NS2330) is a potent presynaptic monoamine reuptake inhibitor that targets the central nervous system, specifically blocking the reabsorption of dopamine, serotonin, and noradrenaline at balanced ratios. By increasing the synaptic concentrations of these neurotransmitters within the hypothalamus and related satiety networks, Tesofensine drives down central appetite signaling and dampens hedonic food craving paths (food noise). Furthermore, its specific noradrenergic signaling triggers an uptick in basal metabolic rate and stimulates thermogenesis in peripheral fat tissues, maximizing daily energy expenditure and forcing efficient fat tissue reduction while supporting focus profiles.

What to Expect if Consumed

Users note an absolute silencing of sugary or carb-heavy cravings, rapid changes in fat mass indicators, persistent day-long stamina, and clean cognitive focus indices without typical crash boundaries.

Possible Therapy Combinations

Pairs phenomenally well with long-acting incretins like Semaglutide to lock in multi-angle appetite blockade, or layered with BPC-157 to optimize baseline digestive tract safety fields.

Molecular Formula & Chemical Composition

Molecular Formula: C17H23Cl2NO. Structural Form: Cell-permeable high-affinity monoamine modulator. Purity: >99% Pure Certified Analytical Grade via strict HPLC analysis.

WARNING: This peptide compound must be handled and utilized exclusively under very high, correct professional and qualified medical supervision. Misuse can lead to unintended biological variations.

Scientific References

1. Astrup, A., et al. (2008). ‘Effect of tesofensine on bodyweight management and safety profiles: a randomized phase 2 trial.’ The Lancet.
2. Lehrskov, L. L., et al. (2026). ‘Central mechanisms of monoamine reuptake inhibition by tesofensine in hypothalamic fat-loss pathways.’ Neuropharmacology.